亚洲综合一区二区三区无码,野花社区日本在线观看免费观看3,亚洲小说区图片区另类春色,日韩人妻无码一区二区三区综合部

服務(wù)熱線

15021010459
產(chǎn)品中心
當(dāng)前位置:主頁(yè) > 產(chǎn)品中心 > > 干細(xì)胞無(wú)血清培養(yǎng)基 >InvivoGen tlrl-pm2s-1 Pam2CSK4 TLR2(6) agonist TLR2(6) 拮抗劑 阻斷劑

InvivoGen tlrl-pm2s-1 Pam2CSK4 TLR2(6) agonist TLR2(6) 拮抗劑 阻斷劑

簡(jiǎn)要描述:TLR2(6) agonist TLR2(6) 拮抗劑,與TLR2(6)蛋白競(jìng)爭(zhēng)性結(jié)合,阻止其他蛋白與他結(jié)合。Pam2CSK4 Synthetic diacylated lipoprotein Pam2CSK4 is a synthetic diacylated lipopeptide (LP).

  • 產(chǎn)品型號(hào):tlrl-pm2s-1
  • 廠商性質(zhì):代理商
  • 更新時(shí)間:2025-02-13
  • 訪  問  量:2516
詳細(xì)介紹

TLR2(6) agonist TLR2(6) 拮抗劑,與TLR2(6)蛋白競(jìng)爭(zhēng)性結(jié)合,阻止其他蛋白與他結(jié)合。Pam2CSK4 Synthetic diacylated lipoprotein Pam2CSK4 is a synthetic diacylated lipopeptide (LP).

Pam2CSK4

美國(guó)InvivoGen Invivogen主要提供抗生素,轉(zhuǎn)染試劑,細(xì)胞因子,細(xì)胞系,質(zhì)粒等產(chǎn)品??股睾w了細(xì)胞培養(yǎng)、篩選全系列,如Blasticidin S,Hygromycin B, Phleomycin, Primocin,   Zeocin等細(xì)胞分選常用抗生素。尤其以抗細(xì)胞支原體污染的抗生素Plasmocin™zui為出名,該抗生素因其性能受到客戶*好評(píng)。

Synthetic diacylated lipoprotein
Pam2CSK4 is a synthetic diacylated lipopeptide (LP). According to the current model, diacylated LPs induce signaling through TLR2/6.
However, it was also reported that Pam2CSK4 induces signaling in a TLR6-independent manner. This finding suggests that both the lipid and peptide part of lipoproteins take part in the specificity of recognition by TLR2 heterodimers.
Catalog code change notification

The catalog code of Pam2CSK4 has been changed from "tlrl-pam2" to "tlrl-pm2s" to notify a modification in the production process. Pam2CSK4 "tlrl-pam2" was synthesized in a liquid form, Pam2CSK4 "tlrl-pm2s" is produced by solid-phase peptide synthesis.
Specifications

Specificity: TLR2(6) agonist
Working concentration: 1 - 100 ng/ml
Molecular formula: C65H126N10O12S, 2TFA
Molecular weight: 1271.85
Endotoxin level:  <0.001 EU/μg
Solubility: 1 mg/ml in water
Details


Contents
• Pam2CSK4 is available in two quantities:

- 100 μg: tlrl-pam2
- 1 mg: tlrl-pam2-1

• 1.5 ml sterile endotoxin-free water

Pam2CSK4 is provided as a lyophilized powder and shipped at room temperature. Store at 4°C. Upon resuspension prepare aliquots of Pam2CSK4 and store at 4°C for short term storage or -20°C for long storage. Resuspended product is stable 1 month at 4°C and 6 months at -20°C when properly stored.
Description
Pam2CSK4 is a synthetic diacylated lipopeptide (LP). Bacterial lipoproteins are strong immune modulators that activate early innate host responses after infection. LP analogs of these lipoproteins signal either through TLR2/1 or TLR2/6 heterodimers. According to the current model, triacylated LP like Pam3CSK4, are recognized by TLR2/1, whereas diacylated LP, such as FSL1, induce signaling through TLR2/6. However, it was recently reported that diacylated LP, such as Pam2CSK4, induce signaling in a TLR6-independent manner [1]. This finding suggests that both the lipid and peptide part of lipoproteins take part in the specificity of recognition by TLR2 heterodimers.

1. Buwitt-Beckmann U. et al., 2005. Toll-like receptor 6-independent signaling by diacylated lipopeptides. Eur J Immunol. 35(1):282-9.
Citations
Recent articles using Pam2CSK4

 

•2011 - J Immunol., 186: 5916 - 5926
Synergistic interactions of TLR2/6 and TLR9 induce a high level of resistance to lung infection in mice.
 Duggan JM, You D, Cleaver JO, Larson DT, Garza RJ, Guzman Pruneda FA, Tuvim MJ, Zhang J, Dickey BF, Evans SE.
Free article
•2012 - Immunity, 36(3):464-476
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages.
 Khare S, Dorfleutner A, Bryan NB, Yun C, Radian AD, de Almeida L, Rojanasakul Y, Stehlik C

•2011 - Clin Vaccine Immunol., 18(11):1834-1844
Assessment of Lactobacillus gasseri as a candidate oral vaccine vector
 Stoeker L, Nordone S, Gunderson S, Zhang L, Kajikawa A, LaVoy A, Miller M, Klaenhammer TR, Dean GA
Free article

 


產(chǎn)品咨詢

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說(shuō)明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7
推薦產(chǎn)品

2025 版權(quán)所有 © 重慶市華雅干細(xì)胞技術(shù)有限公司  備案號(hào):渝ICP備14000349號(hào)-4 sitemap.xml 管理登陸 技術(shù)支持:化工儀器網(wǎng)

地址:重慶市江北區(qū)金渝大道153號(hào)8棟20-14 傳真:023-63419626 郵件:sales@ys-bio.com

重慶市華雅干細(xì)胞技術(shù)有限公司主要經(jīng)營(yíng)干細(xì)胞研究 干細(xì)胞治療產(chǎn)品 生物試劑 實(shí)驗(yàn)耗材 藥物研發(fā)等產(chǎn)品。

關(guān)注我們

服務(wù)熱線

400-021-2200

掃一掃,關(guān)注我們

欧美熟妇vivoe精品| 丰满熟妇乱又伦| 上司人妻互换hd无码中文字幕| 八戒八戒神马在线电影免费| 欧美亚洲国产精品久久高清| 精品少妇爆乳无码av无码专区| 亚洲一区精品二人人爽久久| 免费av视频在线观看| 再深点灬舒服灬受不了了视频| 自己在线观看免费高清| 肉妇春潮干柴烈火myfducc| 亚洲最大成人网| 久久亚洲美女精品国产精品| 老熟女BBW搡BBBB搡| 人妻办公室被强奷hd| 国产三级精品三级| 精品精品国产高清a级毛片| 7777久久亚洲中文字幕| julia无码人妻中文字幕在线| 人妻在线日韩免费视频| 亚洲日韩激情无码一区| 男男被一根又一根h强迫np| 亚洲国产成人久久精品| 人妻巨大乳hd免费看| 性色av无码久久一区二区三区| 亚洲日韩精品一区二区三区无码 | 天堂资源官网在线资源| 国产精品永久免费视频| 久久久无码av精品亚洲a片软件| 国产av无码国产av毛片| 成人午夜又粗又硬又长| 丝袜灬啊灬快灬高潮了AV| 久久99精品久久久久婷婷暖| 亚洲日日做日日谢日日鲁| 国产精品久久毛片| 亚洲精品久久久无码av片软件| 韩国一区二区三免费看| 亚洲色婷婷久久精品av蜜桃| 亚洲性爱视频| 亚洲AV无码乱码在线观看,不卡| 中文字幕一区二区人妻|